Biost® contains manganese and veal bone PMG™ extract to support cellular and skeletal health.*
Contains veal bone PMG™ extract, which provides a unique profile of minerals, nucleotides, and peptides
Promotes healthy bone and teeth*
What is a Protomorphogen™ extract?
Protomorphogen™ extracts are specific material extracted from animal glands and organs through a complex, multistep process to retain what Standard Process founder Dr. Royal Lee termed “cellular determinants.” Current laboratory methods have confirmed that these proprietary extracts contain minerals, nucleotides (the components of nucleic acids like RNA and DNA), and peptides (short chains of amino acids).*
Why is this extract used in supplements?
Dr. Lee created nutrition products that incorporated ideal sources of nutrition from both vegetables and animals. Veal bone is a complex raw material. In animals, as in humans, bones support white and red blood cell generation and act as a depot for minerals needed by the body. Veal bone PMG™ extract is designed to distill the complexity of this tissue to support human bone health.*
How does the manganese in this product support health?
Manganese is necessary for bone growth, development, and replacement.1, 2Manganese is one of several trace elements necessary for bone health.3Manganese helps to form cartilage and is required to synthesize bone.4Manganese is also necessary (in small quantities) for protein and fat metabolism.5 Manganese supports healthy nerves and strengthens immunity while also playing a role in blood sugar regulation and energy production.6Manganese affects enzymes involved in the synthesis of glycosaminoglycans, which are important structural components in connective and other tissue that promote the health and maintenance of ligaments and tendons.7, 8, 9*
Manganese is one of the few nutrients found at high levels in Standard Process products. It supports tissues rich in mitochondria, like bone and muscle.10 These tissues contain higher amounts of manganese relative to other body structures. Keep in mind that manganese absorption is reduced with age; for example, in a study of the general U.S. population, blood manganese levels were lower with older age.11*
This product contains less than 20 parts per million per the suggested use listed on each product label.
1. Kehl-Fie TE, Skaar EP. 2010. Nutritional immunity beyond iron: a role for manganese and zinc. Curr Opin Chem Biol 14:218-224.
2. Zofková I, Nemcikova P, Matucha P. 2013. Trace elements and bone health. Clin Chem Lab Med. 51(8):1555-61.
3. Ehrlich SD. 2011. Manganese. University of Maryland Medical Center. View Report.
4. See note 1 above.
5. Watts DL. 1990. The Nutritional Relationships of Manganese. J Orthomolecular Med 5:219-222.
6. See note 1 above.
7. Kalea AZ, Lamari FN, Theocharis AD, Schuschke DA, Karamanos NK, Klimis-Zacas DJ. 2006. Dietary manganese affects the concentration, composition and sulfation pattern of heparan sulfate glycosaminoglycans in Sprague-Dawley rat aorta. Biometals. 19(5):535-46.
8. Bolze MS, Reeves RD, Lindbeck FE, Kemp SF, Elders MJ. 1985. Influence of manganese on growth, somatomedin and glycosaminoglycan metabolism. J Nutr. 115(3):352-8.
9. Naithani M, Bharadwaj J, Darbari A. 2014. Magnesium: The fifth electrolyte. J Med Nutrit Nutraceuticals. 3:66-72.
10. Prashanth L, et al. 2014. A review on role of essential trace elements in health and disease. J Ntr Univ Health Sci. 4:75-82
11. Oulhote Y, Mergler D, Bouchard MF. 2014. Sex- and age-differences in blood manganese levels in the U.S. general population: national health and nutrition examination survey 2011-2012. Environ Health. 13:87.
12. Zofková I, Nemcikova P, Matucha P. 2013. Trace elements and bone health. Clin Chem Lab Med. 51(8):1555-61.