Cataplex® D supports bone health, mineral absorption, the immune system, and cellular processes.*
Encourages healthy calcium absorption from the intestinal tract into the blood
Supports healthy immune system response function
Supports and maintains healthy bone density
Provides vitamin D, which is needed by almost every cell in the body for development and transcription*
How does this product support healthy immune function?
Vitamin D, as contained in Cataplex D, is recognized as fundamental to the development and control of important cells in the immune system, including lymphocytes1 and macrophages.2, 3 Vitamin D acts on immune cells, affecting the production of a variety of chemical messengers.4 Adequate levels of vitamin D help to maintain the integrity of the immune system.5, 6, 7, 8*
How does this product support healthy bones?
Cataplex D provides vitamin D, which helps control blood levels of calcium and phosphate, which are raw materials used by bone-forming cells to produce woven bone for growth and normal repair.9 Vitamin D maintains calcium and phosphate levels to ensure correct mineralization of bones and plays a crucial role in development and maintenance of a healthy skeleton.10, 11 Vitamin D also plays a role in calcium absorption.12 The absorption of calcium in the intestine is regulated by vitamin D,13 and vitamin D deficiency causes reduced calcium absorption in the gut.14 Vitamin D requires several other nutrients for assimilation, including calcium and vitamin A. The human body contains more calcium than any other mineral. Approximately 99 percent of that calcium is used in the bones and teeth.15*
How does this product support cellular processes?
Vitamin A, as contained in Cataplex D, regulates numerous cellular processes. Metabolites of vitamin A regulate the expression of many genes involved in cell growth and differentiation, development, and balanced physiological processes.16Calcium and phosphorus are involved in many bodily processes, and maintaining the delicate balance between calcium and phosphorus is necessary for proper bone health and maintenance of cells and tissue throughout the body.17*
This product contains less than 20 parts per million per the suggested use listed on each product label.
Vegetarian (lacto-ovo)
1. Hewison M. 2012. Vitamin D and immune function: an overview. Proc Nutr Soc. 71:50-61.
2. Rosen CJ, Adams JS, Bikle DD, et al. 2012. The Nonskeletal Effects of Vitamin D: An Endocrine Society Scientific Statement. Endocr Rev. 33(3):456492.
3. Hewison M. 2010. Vitamin D and the immune system: new perspectives on an old theme. Endocrinol Metab Clin North Am. 39(2):365-379.
4. Ross AC, Taylor CL, Yaktine AL, Del Valle HB. 2011. Dietary Reference Intakes for Calcium and Vitamin D. Institute of Medicine, National Academies Press, Washington, DC, p. 90.
5. Hossein-nezhad A, Holick MF. 2013. Vitamin D for Health: A Global Perspective. Mayo Clin Proc. 88(7):720-755.
6. Khazai N, Judd SE, Tangpricha V. 2008. Calcium and Vitamin D: Skeletal and Extraskeletal Health. Curr Rheumatol Rep. 10(2):110-117.
7. Prietl B, Treiber G, Pieber TR, Amrein K. 2013. Vitamin D and Immune Function. Nutrients. 5(7):2502-2521.
8. Hewison M. 2010. Vitamin D and the immune system: new perspectives on an old theme. Endocrinol Metab Clin North Am. 39(2):365-379.
9. Bikle DD. 2012. Vitamin D and Bone. Curr Osteoporos Rep. 10(2):151-159.
10. Wacker M, Holick MF. 2013. Vitamin D: Effects on Skeletal and Extraskeletal Health and the Need for Supplementation. Nutrients. 5(1):111-148.
11. Laird E, Ward M, et al. 2010. Vitamin D and Bone Health; Potential Mechanisms. Nutrients. 2(7):693-724.
12. Khazai N, Judd SE, Tangpricha V. 2008. Calcium and Vitamin D: Skeletal and Extraskeletal Health. Curr Rheumatol Rep. 10(2):110-117.
13. Khazai N, Judd SE, Tangpricha V. 2008. Calcium and Vitamin D: Skeletal and Extraskeletal Health. Curr Rheumatol Rep. 10(2):110-117.
14. Fleet JC, Schoch RD. 2010. Molecular Mechanisms for Regulation of Intestinal Calcium Absorption by Vitamin D and Other Factors. Crit Rev Clin Lab Sci. 47(4):181-195.
15. Alpert P.T. 2013. Calcium, a necessary mineral for proper body function: Facts you should know. Home Health Care Mgt Practice 25:239-241.
16. Tanoury ZA, Piskunov A, Rochette-Egly C. 2013. Vitamin A and retinoid signaling: genomic and nongenomic effects. J Lipid Res. 54(7):1761-1775.
17. Ehrlich SD. 2013. Phosphorus. View Report.
18. View Report.
19. Scientific Report of the 2015 Dietary Guidelines Advisory Committee. 2015. View Report.