Cataplex G maintains nerve health and provides a calmative effect on the nervous system.*
Encourages healthy parasympathetic nerve function
Supports healthy liver function
Supports brain and nervous system function
Supports the body’s metabolism
Provides coenzymes and cofactors needed for cellular function
Good source of antioxidant vitamin C*
How do the B vitamins in Cataplex G support health?
Cataplex G contains the important B vitamins riboflavin (B2), niacin (B3), and pyridoxine (B6). The members of the B-complex family of vitamins are responsible for many important physiological processes concerned with both mental health and physical well-being.*
Riboflavin contributes to the production of cellular energy, and niacin is a coenzyme essential for cell respiration, protein and carbohydrate metabolism, and lipid synthesis. Vitamin B6 is an essential nutrient comprised of six related compounds1 that support the healthy functioning of the nervous system,2 cellular metabolism,3 and immune system4 as well as formation of red blood cells. (A vitamin B6 compound, pyridoxal 5-phosphate, enables the first step in the synthesis of heme, the molecule that binds to oxygen in red blood cells.5) In addition, vitamin B6 is involved in the function of several essential chemical reactions in the body, including amino acid6 and red blood cell metabolism (due to heme synthesis).7 Vitamin B6 also is required for the synthesis of the nucleic acids RNA and DNA, molecules that carry genetic instructions for normal cellular growth and reproduction.*
How does Cataplex G provide antioxidant support?
Cataplex G provides a good source of antioxidant vitamin C and riboflavin. Riboflavin is required (in the flavin adenine dinucleotide coenzyme form) by an enzyme, glutathione reductase, that converts oxidized glutathione to the reduced form.8 Reduced glutathione acts as an antioxidant in various types of cells and protects the body against oxidative stress.9 Vitamin B6 may also be involved in the rate of glutathione synthesis in red blood cells, although the effects of vitamin B6 deficiency on the concentration of glutathione in red blood cells may vary from person to person.10*
1. Institute of Medicine. 1998. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academies Press, Washington, DC. http://www.ncbi.nlm.nih.gov/books/NBK114313/
2. Dakshinamurti S, Dakshinamurti K. 2015. Antihypertensive and neuroprotective actions of pyridoxine and its derivatives. Can J Physiol Pharmacol. 93(12):1083-90.
3. Gregory JF, et al. 2013. Metabolomic Analysis Reveals Extended Metabolic Consequences of Marginal Vitamin B-6 Deficiency in Healthy Human Subjects. PLoS One. 8(6):e63544.s
4. Calder PC, Kew S. 2002. The immune system: a target for functional foods? Br J Nutr. 88 Suppl 2:S165-77.
5. Layer G, Reichelt J, Jahn D, Heinz DW. 2010. Structure and function of enzymes in heme biosynthesis. Protein Sci. 19(6):1137–1161.
6. See note 1 above.
7. See note 5 above.
8. Ashoori M, Saedisomeolia A. 2014. Riboflavin (vitamin B2) and oxidative stress: a review. British J Nutrit. 111:1985-1991.
9. Ibid.
10. Lamers Y, O'Rourke B, Gilbert LR, Keeling C, Matthews DE, Stacpoole PW, Gregory JF. 2009. Vitamin B-6 restriction tends to reduce the red blood cell glutathione synthesis rate without affecting red blood cell or plasma glutathione concentrations in healthy men and women. Am J Clin Nutr. 90(2):336-43.