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High quality St John's Wort contains the naphthodianthrones hypericin and pseudohypericin (hypericins), flavonoids, phenolics and other compounds. St John's Wort High Grade 1:2 contains a higher percentage of hypericins than the regular St John's Wort product. This product contains a minimum of 0.4 mg/mL of hypericins to ensure optimal strength and quality. The phytochemicals in St John's Wort High Grade 1:2, particularly the naphthodianthrones, work together to:
- calm the nerves and restore balance in temporary mood swings
- support healthy emotional and nervous system response following stress, prolonged exercise or during menstruation
- support the body's natural ability to cope with the changes of everyday life
- provide a tonic for the nervous system
- ease the effects of occasional stress
- promote optimal immune system response in relation to environmental stresses*
Suggested Use: Dilute 5 mL (approx. 1 teaspoon) in water or juice once per day, or as directed.
St John’s Wort Quality Issues
St John’s Wort is comprised of a wide range of phytochemicals of which the naphthodianthrones (consisting mainly of hypericin and pseudohypericin) are characteristic, while several other constituents are found across a very wide variety of plant species; e.g., chlorogenic acid, flavonoids and biapigenins. Studies have shown that hypericin administered with flavonoid glycosides caused an increase in the bioavailability of hypericin. St John’s Wort extracts containing the flavonoid glycosides but devoid of hypericin and hyperforin have been shown to be pharmacologically active in model systems. Additionally, extracts devoid of hyperforin have been proven effective in clinical trials as have extracts containing hyperforin. In the graph, all extracts contained the same level of napthodianthrones (hypericins), however a wide range of variation was shown for the other constituents when analyzed by HPLC, some extracts having very low levels of all the phytochemicals you would expect in a good quality extract of Hypericum perforatum. MediHerb recognizes the importance of all the other constituents, particularly the oligomeric procyanidins and flavonoids and tests all it’s products using the techniques which allow the identification of these components.